USP 32 NF 27 2009 (United States Pharmacopeia/National Formulary)
by US Pharmacopeia

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Pharmaceutical Preformulation
by Jens T. Carstensen

Pharmaceutical Preformulation
By Jens T. Carstensen

Publisher: Informa HealthCare
Number Of Pages: 320
Publication Date: 1998-07-07
ISBN-10 / ASIN: 1566766907
ISBN-13 / EAN: 9781566766906
Binding: Hardcover

FROM THE PREFACEThis book addresses problems and solutions of formulation and preformulation with which I have concerned myself for 34 years. When I was employed in the pharmaceutical industry I worked at functions, in the 1960’s, which were the precursors of preformulation, and my early publications dealt with such matters. In the following decades advances have been made in methodology and the realm of preformulation has grown. Theory and the way in which problems are viewed have also undergone change. The text deals with the pharmaceutical aspects of preformulation, not the synthetic nor the analytical aspects. It takes its vantage point at the point in time when the pharmaceutical preformulator first obtains a sample of the drug substance, and it explores the physical, chemical and technological aspects that are needed for a full exploration of the potential advantages and disadvantages of the drug substance. It is only through the understanding of underlying principles that adequate exploration can be carried out.

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Inside Pharmacy: The Anatomy of a Profession
by M. Christine Gosselin, Jack Robbins

Inside Pharmacy: The Anatomy of a Profession
By M. Christine Gosselin, Jack Robbins

Publisher: Technomic Publishing Company
Number Of Pages: 134
Publication Date: 1999-10-02
ISBN-10 / ASIN: 1566766796
ISBN-13 / EAN: 9781566766791
Binding: Hardcover

This book traces the evolution of the pharmacist from compounder-dispenser to advisor counselor. It explores the impact on pharmacy of broad sociologic, demographic, and economic trends and examines controversial issues such as professional versus business objectives, managed cost care, coginitive services, pharmaceutical care, and the future roles of pharmacists. Drawing on the literature in sociology and social pathology, the book relates some theoretical constructs to the changing roles of the pharmacist. It includes coverage of pharmaceutical education, disease state management, managed care, and new technologies.

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Pharmacokinetics: Regulatory, Industrial, Academic Perspectives (Drugs and the Pharmaceutical Sciences)
by Peter Welling

Pharmacokinetics: Regulatory, Industrial, Academic Perspectives (Drugs and the Pharmaceutical Sciences)
By Peter Welling

Publisher: Informa HealthCare
Number Of Pages: 512
Publication Date: 1995-04-15
ISBN-10 / ASIN: 0824793781
ISBN-13 / EAN: 9780824793784
Binding: Hardcover

Offering a unique, multidisciplinary approach, this state-of-the-art Second Edition details the rapidly changing role that clinical and non-clinical pharmacokinetics and drug metabolism play in the discovery and development of drug therapies — emphasizing often overlooked regulatory, scientific, and economic issues.

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Handbook of Pharmaceutical Granulation Technology (Drugs and the Pharmaceutical Sciences: a Series of Textbooks and Monographs)
by Dilip M. Parikh

Handbook of Pharmaceutical Granulation Technology (Drugs and the Pharmaceutical Sciences: a Series of Textbooks and Monographs)
By Dilip M. Parikh

Publisher: Marcel Dekker
Number Of Pages: 512
Publication Date: 1997-06-17
ISBN-10 / ASIN: 0824798821
ISBN-13 / EAN: 9780824798826
Binding: Hardcover

This practical guide integrates the basic principles and current industrial practices of pharmaceutical granulation production;discussing state-of-the-art technologies and demonstrating cost-effective approaches to manufacturing solid-dosage forms with content uniformity and consistent physical properties while complying with regulatory requirements.

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Drug Development Process: Increasing Efficiency & Cost Effectiveness (Drugs and the Pharmaceutical Sciences)
by Peter Welling

Drug Development Process: Increasing Efficiency & Cost Effectiveness (Drugs and the Pharmaceutical Sciences)
By Peter Welling

Publisher: Informa HealthCare
Number Of Pages: 447
Publication Date: 1996-08-15
ISBN-10 / ASIN: 0824797272
ISBN-13 / EAN: 9780824797270
Binding: Hardcover

Containing contributions from the many disciplines involved in a drug’s evolution, this timely volume examines the entire pharmaceutical development process, emphasizing approaches to increasing efficiency and reducing costs.

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Pharmaceutical Project Management (Drugs and the Pharmaceutical Sciences, Volume 86)
by Tony Kennedy

Pharmaceutical Project Management (Drugs and the Pharmaceutical Sciences, Volume 86)
By Tony Kennedy

Publisher: Marcel Dekker
Number Of Pages: 290
Publication Date: 1997-10-24
ISBN-10 / ASIN: 0824701119
ISBN-13 / EAN: 9780824701116
Binding: Hardcover

Drawing on the experience of project managers from international pharmaceutical companies, this work reviews up-to-date strategic, operational and organizational procedures for drug development in today’s competitive industry. It includes details of how target product profiles are established and used to direct drug development; and project definition and risk management, including analytical techniques and asset valuation at the project and portfolio levels.

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Pharmaceutical Dosage Forms: Tablets, Vol. 2 (Pharmaceutical Dosage Forms-Tablets)
by Herbert Lieberman, Leon Lachman, Joseph B. Schwartz

Pharmaceutical Dosage Forms: Tablets, Vol. 2 (Pharmaceutical Dosage Forms-Tablets)
By Herbert Lieberman, Leon Lachman, Joseph B. Schwartz

Publisher: Informa Healthcare
Number Of Pages: 640
Publication Date: 1990-03-30
ISBN-10 / ASIN: 0824782895
ISBN-13 / EAN: 9780824782894
Binding: Hardcover

H.H. Lieberman Associates, Inc., Livingston, New Jersey. ‘Tablets’ complete in 3 volumes. Pharmaceutical technology. 15 Contributors. DNLM: 1. Dosage forms.

Summary: Pharmaceutical Suspensions
Rating: 5

General things of Pharmaceutical Suspensions, Stability of this dosage form. Quality assurance of Pharmaceutical suspensions

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Aquaporins (Handbook of Experimental Pharmacology, Volume 190)
by Eric Beitz

Aquaporins (Handbook of Experimental Pharmacology) (Volume 190)
By Eric Beitz

Publisher: Springer
Number Of Pages: 510
Publication Date: 2009-01-01
ISBN-10 / ASIN: 3540798846
ISBN-13 / EAN: 9783540798842
Binding: Hardcover

The aquaporin field has matured at an exceptionally fast pace and we are at the verge to develop serious strategies to therapeutically modulate aquaporin function directly or via regulatory networks. Key prerequisites are available today: i. a considerable (and growing) number of aquaporin crystal structures for the rational design of inhibitory molecules, ii. elaborate molecular dynamics simulation techniques for theoretical analyses of selectivity mechanisms and docking experiments, iii. comprehensive data on aquaporin immunohistochemistry, iv. aquaporin knockout animals for physiological studies, and v. assay systems for compound library screenings. The structure of this volume on aquaporins follows the points laid out above and thus covers the developments from basic research to potential pharmacological use. Situated between pharmacology textbooks and recent scientific papers this book provides a timely overview for readers from the fundamental as well as the applied disciplines.

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Electrochemical Detection in HPLC: Analysis of Drugs and Poisons (Rsc Chromatography Monographs)
by R. J. Flanagan, D Perrett, R Whelpton

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons (Rsc Chromatography Monographs)
By R. J. Flanagan, D Perrett, R Whelpton

Publisher: Royal Society of Chemistry
Number Of Pages: 244
Publication Date: 2005-07-01
ISBN-10 / ASIN: 0854045325
ISBN-13 / EAN: 9780854045327
Binding: Hardcover

Electrochemical Detection in HPLC: Analysis of Drugs and Poisons is the first monograph devoted to the application of this mode of analysis to the assay of exogenous compounds such as drugs in biological fluids and associated areas.

The introductory chapters provide information on basic electrochemistry and HPLC-ED, and on trouble-shooting. The specialized area of thiol analysis is also discussed in detail. Salient practical details of published applications of the technique in analytical toxicology and related areas are provided in a standard format. Alternative techniques are suggested throughout. The emphasis is on the analysis of exogenous compounds, although catecholamines and other endogenous species are discussed in so far as they may be used as drugs.

The practical nature of this book will make it useful to professionals working in the field. It will also be of benefit to analysts wishing to use HPLC-ED in the analysis of biological samples for analytes not specifically covered in the volume.

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Parenteral Quality Control (Advances in Parenteral Sciences, Vol 5)
by Akers

Parenteral Quality Control (Advances in Parenteral Sciences, Vol 5)
By Akers

Publisher: CRC
Number Of Pages: 400
Publication Date: 1993-09-29
ISBN-10 / ASIN: 082479088X
ISBN-13 / EAN: 9780824790882
Binding: Hardcover

This second edition details current methods of testing parenteral quality control and discusses new techniques and emerging trends. It combines principles with practical information on how the tests are conducted, their strengths and limitations, and possible forthcoming changes. Coverage includes global testing requirements; new issues and approaches involving retesting of lots that failed initial sterility tests; and new technologies such as barrier systems for conducting sterility testing.

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Drugs: From Discovery to Approval, 2nd edition
by Rick Ng

Drugs: From Discovery to Approval
By Rick Ng

Publisher: Wiley-Blackwell
Number Of Pages: 466
Publication Date: 2008-12-03
ISBN-10 / ASIN: 047019510X
ISBN-13 / EAN: 9780470195109
Binding: Hardcover

The new edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products. Concise and easy to read, the book quickly introduces basic concepts, then moves on to discuss target selection and the drug discovery process for both small and large molecular drugs. The new edition features many key enhancements, including Key Points, Chapter Summary, and Review Questions in each chapter, Answers to Review Questions provided in a book-end appendix, and one or two carefully selected “mini” case studies in each chapter.

Summary: Good book to discover the world of drug discovery
Rating: 3

If you are not a specialist in the field of drug discovery but need nevertheless to have a comprehensive knowledge of the process that starts at the discovery of a potential new drug and ends at the registration of the drug with a regulatory agency, this book is for you. The book is full of flowcharts and illustrations that help you to understand the process. It’s certainly not a book for specialists, but can be really helpful for lawyers, contracts officers and everyone who works in the drug discovery industry.

Summary: A simple, yet comprehensive introduction
Rating: 3

It’s tough to learn quickly about the complexities of pharma R&D. This is a useful guide for those new to the industry and fills in the gaps for those more experienced. Like all books of its type, it will age quite rapidly in an sector undergoing rapid scientific and organizational change.

Summary: An easy way to understand a complex process
Rating: 5

I work in an organization that supports advanced gene therapy research that may lead to new therapies for chronic and life threatening diseases, but I am not a scientist. As a communicator, I needed to understand the long and arduous journey from discovery to pre-clinical research, to FDA-approved clinical manufacturing, and to human clinical trials. This book was excellent in helping me understand both the research and the regulatory environment.

The author says it best in the introduction, “The intention of this book is to provide an overview about how a drug is discovered, the amount of and types of laboratory tests that are performed, and the conduct of clinical trials before a drug is ready to registered for human use.” The author also fully explains the role of regulatory authorities in these processes.

The book includes chapters on:
Drug discovery
Drug development and preclinical studies
Clinical trials
Good Manufacturing Practice

You’ll also learn about things like toxicology studies, pharmacodynamics, and pharmacokinetics, and Investigational New Drug applications. Although the book contains some technical discussions and exhibits, the author has a logical and easy-to-understand way of presenting the information.

If, like me, you need to get a better understanding of process of getting basic drug research to the market, this book is for you.

Summary: Broad coverage with little in-depth detail
Rating: 3

This book is written to cover a broad range of topics related to the drug discovery and approval process. Since so many topics are covered, there is very little in-depth coverage on any particular topic. It’s suitable people who don’t have any serious scientific training or experience in the industry. If you are looking for a high-level overview, this is a good book. If you would like more detailed information about any specific topic, you should probably look elsewhere. Some of the explaintions are over simplied in order for the average reader to understand. Much of the material covered in the book can be found in much greater detail by visiting the fda site or googling for the code of federal regulations. But if you do not what the FDA is or what CFR stands for, this book is probably right for you.

Summary: Good overview of the drug development and regulatory process
Rating: 5

This is a very clear and concise review of the drug development process as well as the regulatory issues. It is well organized and well written. It is not a “behind the scenes” nitty-gritty book, but will help anyone who wants to understand the process.

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Animal and Translational Models for CNS Drug Discovery, Volume 1-3 (Animal and Translational Models for Cns Drug Discovery)
by Robert A. McArthur, Franco Borsini

Animal and Translational Models for CNS Drug Discovery, Volume 1-3 (Animal and Translational Models for Cns Drug Discovery)
By Robert A. McArthur, Franco Borsini

Publisher: Academic Press
Number Of Pages: 1376
Publication Date: 2008-10-31
ISBN-10 / ASIN: 012373861X
ISBN-13 / EAN: 9780123738615
Binding: Hardcover

The use of appropriate models can minimize the number of drug candidates that later fail in human trials by accurately predicting the efficacy and the toxicity of each compound. This can be improved with more informed selection of the appropriate models. This three-volume set provides specific guidelines to selecting the appropriate non-human models for trials in the drug discovery and development process. It offers a unique perspectice from the three principle players in the drug discovery process: Industry, Academic, Government, and Clinical.

Each volume is devoted to specific disorders in three scientific fields: Psychiatric, Neurological, and Reward Deficit.

* Details for each disorder on how to analyze and determine what the results mean to the overall drug discovery/development process
* Real-life trial case studies demonstrate how to move to human clinical trial phase
* All volumes also sold individually

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The Canadian Encyclopedia of Natural Medicine
by Sherry Torkos

Canadian Encyclopedia of Natural Cures

Publisher: John Wiley & Sons Inc
Number Of Pages: 400
Publication Date: 2009-02-28
ISBN-10 / ASIN: 0470839082
ISBN-13 / EAN: 9780470839089
Binding: Paperback

Natural solutions for living a clean and healthy life

Health consciousness is an area of transformational and unprecedented growth in the North American public today. More and more people are seeking alternative solutions to conventional medical practices. For many, a natural approach to healing everything from common ailments to serious diseases is preferable when compared to the invasive medical procedures and prescription drugs that abound.

Sherry Torkos, one of Canada’s leading pharmacists is widely regarded for her knowledge of complementary medicine. Her latest book, The Canadian Encyclopedia of Natural Cures, is the definitive source for alternative health care for Canadians; it is totally comprehensive and easy-tofollow, providing natural cures for everyday problems such as insect bites and muscle aches, as well as for serious chronic disorders such as osteoporosis, Parkinson’s disease, and diabetes. Torkos emphasizes the role of lifestyle, nutrition, exercise and supplements in optimizing health and preventing disease. This book features a detailed A to Z reference of ailments and disease, with the latest information on the natural cures that have been proven to assist in their treatment. Detailed information will also advise readers of potential drug interactions that can occur when supplements are taken alongside prescribed medications.

Canadians seeking to create a more holistic and personalized health program for themselves and for their families will turn to this reference time and time again.

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Vitamin E in Health and Disease: Biochemistry and Clinical Applications
by Lester Packer

Vitamin E in Health and Disease: Biochemistry and Clinical Applications
By Lester Packer

Publisher: CRC
Number Of Pages: 1024
Publication Date: 1992-10-30
ISBN-10 / ASIN: 0824786920
ISBN-13 / EAN: 9780824786922
Binding: Hardcover

University of California, Berkeley. Comprehensive volume of state-of-the-art vitamin E research, for biochemists, physiologists, and pharmacologists. Topics include natural occurrence and tissue levels, chemistry, biochemistry, cell biology, pharmacology, and medical applications. Half-tone illustrations.

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cGMP: Generators, Effectors and Therapeutic Implications (Handbook of Experimental Pharmacology) (Volume 191)
by Harald H. H. W. Schmidt, Franz Hofmann, Johannes-Peter Stasch

cGMP: Generators, Effectors and Therapeutic Implications (Handbook of Experimental Pharmacology) (Volume 191)
By Harald H. H. W. Schmidt, Franz Hofmann, Johannes-Peter Stasch

Publisher: Springer
Number Of Pages: 583
Publication Date: 2009-01-01
ISBN-10 / ASIN: 3540689605
ISBN-13 / EAN: 9783540689607
Binding: Hardcover

After the discovery of endogenous NO formation in the late ’80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.

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Pharmaceutical Biotechnology, Second Edition
by Michael J. Groves (Editor)

Pharmaceutical Biotechnology, Second Edition
By Michael J. Groves

Publisher: CRC
Number Of Pages: 432
Publication Date: 2005-08-29
ISBN-10 / ASIN: 0849318734
ISBN-13 / EAN: 9780849318733
Binding: Hardcover

Since the publication of the first edition of Pharmaceutical Biotechnology over a decade ago, a not-so-subtle shift in the meaning of the term “biotechnology” has occurred. It has come to mean something very specific, namely the development of drug substances with large protein and polypeptide molecules. These substances can be used as drugs in their own right but may also be used to manipulate cellular DNA in order to produce a required molecule that is believed to have desirable properties in the treatment of a disease. Accordingly, the second edition of this popular text reflects that change of definition by including new material that explores the development of these protein-based therapeutic substances. See what’s new in the Second Edition: · Expanded coverage of the formulation of proteins · Additional information on proteins used as drug delivery systems · Detailed discussion of interactions between proteins and phospholipids · Increased information on proteomics and gene therapy · Exploration of pulmonary administration and oral delivery of proteins · A broad review of vaccines · Discussion of genetic engineering and genomics · Challenges and issues involved in the development and the production of a drug

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Clinical Handbook of Mindfulness (Handbook of Experimental Pharmacology)
by Jon Kabat-Zinn

Clinical Handbook of Mindfulness (Handbook of Experimental Pharmacology)
By Jon Kabat-Zinn

Publisher: Springer
Number Of Pages: 608
Publication Date: 2008-11-13
ISBN-10 / ASIN: 0387095926
ISBN-13 / EAN: 9780387095929
Binding: Hardcover

Over the last two decades, Eastern thinking has provided a rich counterpart to traditional conceptualizations of psychotherapy. Of central importance, the Buddhist practice of mindfulness, producing a non-judgmental state of self-observation, has served as the inspiration for newly effective interventions. The Clinical Handbook of Mindfulness offers professionals a welcome perspective on this pivotal concept and the ways that it can be used.

A clearly written, up-to-date review and theory-to-practice guide, this volume explores the role of mindfulness (and related concepts in meditation, acceptance, and compassion) and its potential for treating a range of frequently encountered psychological problems.

Key features of the Handbook: (1) A neurobiological review of how mindfulness works. (2) Strategies for engaging patients in practicing mindfulness. (3) Tools and techniques for assessing mindfulness. (4) Interventions for high-profile conditions, including depression, anxiety, trauma. (5) Special chapters on using mindfulness in oncology and chronic pain. (6) Interventions specific to children and elders. (7) Unique applications to inpatient settings. (8) Issues in professional training. (9) Appendix of exercises.

The Clinical Handbook of Mindfulness features some of the leading researchers in the field as chapter authors, and will have wide appeal among clinicians, researchers, and scholars in mental health. Its potential for application makes it an excellent reference for students and trainees.

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The Pharmacy Practice Handbook of Medication Facts
by Harold L. Kirschenbaum, Michelle Kalis

The Pharmacy Practice Handbook of Medication Facts
By Harold L. Kirschenbaum, Michelle Kalis

Publisher: CRC
Number Of Pages: 783
Publication Date: 2000-01-05
ISBN-10 / ASIN: 1566767628
ISBN-13 / EAN: 9781566767620
Binding: Hardcover

Because of the rapidly increasing number of marketed pharmacologic agents, professionals are finding it increasingly difficult to provide colleagues and patients with the types of patient-oriented information they need. You need a handbook with the essential data in one, easy to reference format. Good news - The Pharmacy Practice Handbook of Medication Facts is the answer, THE one source for medication facts. The handbook provides the latest information about prescription medications, including counseling, in a clear, concise and easily portable form. For quick reference, the information is presented in a tabular format that includes: generic/trade names, usual adult dosages, contraindications, major adverse effects and more. The appendices provide additional information, including text/graphics suitable for patient counseling sessions. The Pharmacy Practice Handbook of Medication Facts is an invaluable source for everyone in the health care profession, including pharmacy students, pharmacists, physicians and physician assistants.

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