Drug Discovery and Development for Alzheimer’s Disease (2000)
by: Howard M. Fillit MD, Alan W. O’Connell PhD

Drug Discovery and Development for Alzheimer’s Disease (2000)
By Howard M. Fillit MD, Alan W. O’Connell PhD

Publisher: Springer Publishing Company
Number Of Pages: 280
Publication Date: 2001-12-15
ISBN-10 / ASIN: 082611542X
ISBN-13 / EAN: 9780826115423

Product Description:

(Institute for the Study of Aging) First volume in a new annual series presents the latest findings of an international group of academic and biotechnological researchers. Topics range from early detection programs focusing on genetic factors to the use of telephonic screening and MRIs. DNLM: Alzheimer Disease–diagnosis–Congresses.

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Carbohydrate-based Drug Discovery, 2 Vol Set
by: Chi-Huey Wong

Carbohydrate-based Drug Discovery
By Chi-Huey Wong

Publisher: Wiley-VCH
Number Of Pages: 980
Publication Date: 2003-11-14
ISBN-10 / ASIN: 3527306323
ISBN-13 / EAN: 9783527306329

Product Description:

This handbook presents the latest knowledge on carbohydrate chemistry and biochemistry so as to exploit the full potential of this diverse compound class for the development of novel active substances. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential. Topics include the following:

Chemical synthesis of carbohydrates
Carbohydrate biosynthesis and metabolism
Carbohydrate analysis
Cellular functions of carbohydrates
Development of carbohydrate-based drugs
A premier resource for carbohydrate chemists and drug developers, this comprehensive two-volume work contains contributions by more than 50 of the world’s leading carbohydrate chemists.

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Technetium: Chemistry and Radiopharmaceutical Applications
by: Klaus Schwochau

Technetium: Chemistry and Radiopharmaceutical Applications
By Klaus Schwochau

Publisher: Wiley-VCH
Number Of Pages: 446
Publication Date: 2000-05-15
ISBN-10 / ASIN: 3527294961
ISBN-13 / EAN: 9783527294961

Product Description:

This unique handbook provides a comprehensive survey of the present status of Technetium chemistry and its radiopharmaceutical applications. All Technetium aspects such as
· natural and artificial occurence in the environment,
· isotopes and isomers,
· analytical chemistry and electrochemistry,
· thermodynamic data, stability and reactivity,
· intermetallic and binary compounds, and predominantly
· complex chemistry, and
· radiopharmacy
are presented in an clear and precise manner. This outstanding presentation allows both experts and non-experts a quick access to the subject. Therefore this handbook is an indispensable reference for researchers at universities and research centers, in the nuclear medicine and radiopharmaceutical industries as well as consultants in government and environmental agencies.

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NMR Spectroscopy in Pharmaceutical Analysis
by: Iwona Wawer, Bernd Diehl, Ulrike Holzgrabe
en

0444531734 9780444531735 9780080558196

NMR Spectroscopy in Pharmaceutical Analysis
By Iwona Wawer, Bernd Diehl, Ulrike Holzgrabe

Publisher: Elsevier Science
Number Of Pages: 528
Publication Date: 2008-10-10
ISBN-10 / ASIN: 0444531734
ISBN-13 / EAN: 9780444531735
Binding: Hardcover

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized.
Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis.
Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples.

combines theory, techniques, and concrete applicationsall of which closely resemble the laboratory experience
considers international pharmacopoeias, addressing the concern for licensing
features the work of academics and researchers, appealing to a broad readership

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