NMR Spectroscopy in Pharmaceutical Analysis
by: Iwona Wawer, Bernd Diehl, Ulrike Holzgrabe
en
0444531734 9780444531735 9780080558196
NMR Spectroscopy in Pharmaceutical Analysis
By Iwona Wawer, Bernd Diehl, Ulrike Holzgrabe
Publisher: Elsevier Science
Number Of Pages: 528
Publication Date: 2008-10-10
ISBN-10 / ASIN: 0444531734
ISBN-13 / EAN: 9780444531735
Binding: Hardcover
For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized.
Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis.
Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples.
combines theory, techniques, and concrete applicationsall of which closely resemble the laboratory experience
considers international pharmacopoeias, addressing the concern for licensing
features the work of academics and researchers, appealing to a broad readership
Please Login or Register to read the rest of this content.
Random Posts
- The Jak-Stat Pathway in Hematopoiesis (Molecular Biology Intelligence Unit, 20) (0)
- Interactive Physiology 9-system Suite - Human Anatomy and Physiology (0)
- Antibiotic Therapy for Geriatric Patients (0)
- The Organic Chemistry of Drug Synthesis vol 1-4 (0)
- Catfish Ponds and Lily Pads: Creating and Enjoying a Family Pond (0)
- The Whole Story: Alternative Medicine On Trial? (0)