• ISBN: 9783540735007
• Publisher: Springer
• Edition: 1
• Date: 01 May 2008
• Pages: 186

Protein phosphorylation is an essential post-translational modification that modulates cellcell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups.

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• Author(s): Jill Marsden
• ISBN: 9780333918760
• Publisher: Palgrave Macmillan
• Date: 06 Sep 2002
• Pages: 232

This book explores the imaginative possibilities for philosophy created by Nietzsche's sustained reflection on the phenomenon of ecstasy. From The Birth of Tragedy to his experimental "physiology of art," Nietzsche examines the aesthetic, erotic, and sacred dimensions of rapture, hinting at how an ecstatic philosophy is realized in his elusive doctrine of Eternal Return. Jill Marsden pursues the implications of this legacy for contemporary Continental thought via analyses of such voyages in ecstasy as Kant, Schopenhauer, Schreber, and Bataille.

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• Author(s): Robert Guttmann
• ISBN: 9780333987308
• Publisher: Palgrave Macmillan
• Date: 29 Nov 2002
• Pages: 320

Cybercash refers to the creation and circulation of online money. Guttman applies economic analysis to this electronic money to understand how it will enable the internet to re-establish itself as the dynamic center of the new economy and how this new money form will become the dominant payment mechanism rivaling cash, paper checks or credit cards. This will be the first book to look at the coming era of electronic money within the broader context of the economy.


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• Author(s): Philip A. Fisher
• ISBN: 9780470139493
• Publisher: Wiley
• Date: 03 Aug 2007
• Pages: 213

Paths to Wealth through Common Stocks contains one original concept after another, each designed to greatly improve the results of those who self-manage their investments -- while helping those who rely on professional investment advice select the right advisor for their needs.

Originally written by investment legend Philip A. Fisher in 1960, this timeless classic is now reintroduced by his well-known and respected son, successful money manager Ken Fisher, in a new Foreword.

Filled with in-depth insights and expert advice, Paths to Wealth through Common Stocks expands upon the innovative ideas found in Fisher's highly regarded Common Stocks and Uncommon Profits -- summarizing how worthwhile profits have been and will continue to be made through common stock ownership, and revealing why his method can increase profits while reducing risk. Many of the ideas found here may depart from conventional investment wisdom, but the impressive results produced by these concepts -- which are still relevant in today's market environment -- will quickly remind you why Philip Fisher is considered one of the greatest investment minds of our time.

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• Author(s): Bob Clyatt
• ISBN: 9781413307054
• Publisher: NOLO
• Edition: 2
• Date: 30 Sep 2007
• Pages: 365

Ready to pursue the rest of your life? Get going with Work Less, Live More.

Finalist for The Publishers Marketing Associations Benjamin Franklin Award

Professionally, you're experiencing the success that years of hard work brings -- but the long hours are taking their toll and you're burning out fast.

Fortunately, there is an alternative to the grind: Semi-retirement. Work fewer hours, realize your goals and dreams, spend time with your loved ones-- and do it all years, even decades, before the "normal" retirement age of 65.

With Work Less, Live More and a little planning, you can do it. The book provides a rational investment system based on Nobel Prize-winning research, a safe lifelong withdrawal plan and sensible spending guidelines.

More importantly, the book provides the inspiring stories and insights of many successful early semi-retirees, walking proof that meaningful work-- rather than full-time work-- is both fulfilling and rewarding.

The 2nd edition focuses on every age group -- especially "late bloomers" who may feel way behind. It also includes more information on healthcare issues.

If you're ready to pursue the rest of your life, turn to Work Less, Live More and get going!

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• ISBN: 9780444531681
• Publisher: Elsevier Science
• Edition: 1
• Date: 16 Apr 2008
• Pages: 350

The book "The digestive system in systemic autoimmune diseases" represents the state-of-the-art in the field of digestive disorders in the most common systemic autoimmune diseases.
The volume consists of an introductory chapter on imaging techniques in digestive diseases, followed by eight chapters on digestive manifestations in specific systemic autoimmune diseases. The final five chapters deal with digestive diseases with an autoimmune pathogenesis and systemic manifestations.
International in scope, the table of contents reads like a Who's who in clinical research on systemic autoimmune diseases. More than 20 contributors from the European Union, the United States, Mexico and South Africa share their knowledge in this detailed volume.

*One book of leading international clinical and scientific experts on autoimmune and digestive diseases.
*A practical guide to the identification, diagnosis and treatment of digestive involvement in patients with autoimmune diseases that will be useful for all medical specialties.
*Several diseases and conditions not included in other text books are included, some of which are of recent emergence.
*Each chapter is designed to serve as a Guide to Clinical Practice for each disease.

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