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Posted: September 21st, 2008, 10:39pm CEST by admin

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  • Author(s): Barbara Klein
  • ISBN: 9780814473429
  • Publisher: Amacom
  • Edition: 1
  • Date: 12 Oct 2006
  • Pages: 256
While it can be rewarding to raise an extremely bright child -- quick, curious, sensitive, and introspective -- it’s also a daunting challenge. Parents need insight into their own motivations (as well as those of their children), and the courage and ability to make tough decisions about their child’s development. Raising Gifted Kids will help parents understand and cope with the obstacles they face in raising a gifted child, and help them make the best choices for their son’s or daughter’s growth and happiness. This upbeat and practical book reveals how parents can:

* help develop their child’s potential and self-esteem without pressuring them
* plan their child’s education
* work optimally with schools and teachers
* recognize and prevent problems
* solve family conflicts over parenting issues
* avoid the dangers of living vicariously through their child’s accomplishments
* and much more

Filled with proven solutions to the unique challenges of raising gifted kids, this book is the powerful yet accessible resource parents have long wished for.



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Posted: September 21st, 2008, 10:38pm CEST by admin

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  • Author(s): Peggy Hadden
  • ISBN: 9781581154948
  • Publisher: Allworth Press
  • Date: 30 Oct 2007
  • Pages: 224
Journey through the wit and wisdom of generations of visual artists, photographers, writers, and architects--and discover what makes creative people extraordinary. This compilation of more than 1,000 great quotations, from famous to obscure, celebrates what artist throughout time have said about fame, color, finding inspiration, money woes, beauty, critics, fellow artists, and other provocative topics. The words of Leonardo da Vinci, Georgia O’Keeffe, Paul Cezanne, Ben Shahn, Marcel Duchamp, George Bernard Shaw, Vincent van Gogh, Sigmund Freud, Alexander Calder, Maria Rilke, David Hockney, Andy Warhol, Frank Lloyd Wright, Henri Matisse, Louise Nevelson, and many others are gathered here, in a warm, humorous, and moving collection of wisdom from the masters.





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Posted: September 21st, 2008, 10:38pm CEST by admin

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  • Author(s): Dan Brown
  • ISBN: 9780743538275
  • Publisher: Simon & Schuster Audio
  • Date: 22 Mar 2004
THE ORIGINAL ROBERT LANGDON THRILLER FROM THE #1 BESTSELLING AUTHOR OF

THE DA VINCI CODE

An ancient secret brotherhood.

A devastating new weapon of destruction.

An unthinkable target.

ANGELS & DEMONS

World-renowned Harvard symbologist Robert Langdon is summoned to a Swiss research facility to analyze a cryptic symbol seared into the chest of a murdered physicist. What he discovers is unimaginable: a deadly vendetta against the Catholic Church by a centuries-old underground organization -- the Illuminati. Desperate to save the Vatican from a powerful time bomb, Langdon joins forces in Rome with the beautiful and mysterious scientist Vittoria Vetra. Together they embark on a frantic hunt through sealed crypts, dangerous catacombs, deserted cathedrals, and the most secretive vault on earth...the long-forgotten Illuminati lair.



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Posted: September 21st, 2008, 10:38pm CEST by admin

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  • Author(s): Richard C. Grinold, Ronald N. Kahn
  • ISBN: 9780070248823
  • Publisher: McGraw-Hill
  • Edition: 2
  • Date: 26 Oct 1999
  • Pages: 596

"This new edition of Active Portfolio Management continues the standard of excellence established in the first edition, with new and clear insights to help investment professionals."

-William E. Jacques, Partner and Chief Investment Officer, Martingale Asset Management.

" Active Portfolio Management offers investors an opportunity to better understand the balance between manager skill and portfolio risk. Both fundamental and quantitative investment managers will benefit from studying this updated edition by Grinold and Kahn."

-Scott Stewart, Portfolio Manager, Fidelity Select Equity ® Discipline

Co-Manager, Fidelity Freedom ® Funds.

"This Second edition will not remain on the shelf, but will be continually referenced by both novice and expert. There is a substantial expansion in both depth and breadth on the original. It clearly and concisely explains all aspects of the foundations and the latest thinking in active portfolio management."

-Eric N. Remole, Managing Director, Head of Global Structured Equity, Credit Suisse Asset Management.

Mathematically rigorous and meticulously organized, Active Portfolio Management broke new ground when it first became available to investment managers in 1994. By outlining an innovative process to uncover raw signals of asset returns, develop them into refined forecasts, then use those forecasts to construct portfolios of exceptional return and minimal risk, i.e., portfolios that consistently beat the market, this hallmark book helped thousands of investment managers. Active Portfolio Management, Second Edition , now sets the bar even higher. Like its predecessor, this volume details how to apply economics, econometrics, and operations research to solving practical investment problems, and uncovering superior profit opportunities. It outlines an active management framework that begins with a benchmark portfolio, then defines exceptional returns as they relate to that benchmark. Beyond the comprehensive treatment of the active management process covered previously, this new edition expands to cover asset allocation, long/short investing, information horizons, and other topics relevant today. It revisits a number of discussions from the first edition, shedding new light on some of today's most pressing issues, including risk, dispersion, market impact, and performance analysis, while providing empirical evidence where appropriate. The result is an updated, comprehensive set of strategic concepts and rules of thumb for guiding the process of-and increasing the profits from-active investment management.



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Posted: September 21st, 2008, 10:38pm CEST by admin

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  • Author(s): Christopher Breen
  • ISBN: 9780321486141
  • Publisher: Peachpit Press
  • Edition: 2
  • Date: 13 Nov 2006
  • Pages: 240
iPod users want to start using their devices as soon as they get their hands on them, and this guide shows them how. In these pages, trusted gadget teacher Christopher Breen reveals the secrets to using the leading portable player. This handy guide offers the quickest way to learn how to use the iTunes Store (including the new movie store!), import songs from CDs, and how to pick the right accessories. Readers will also find thorough coverage of the entire iPod family, including the iPod shuffle ($79-1GB; the world's smallest MP3 player), iPod nano ($149-2GB; $199-4GB; $249-8GB), and the updated iPod ($249-30GB and $349-80GB, which holds up to 20,000 songs or 100 hours of video). Along the way, Christopher offers hints for burning CDs, tips for making the most of the device's storage capabilities,and  troubleshooting advice for when the gadgets become uncooperative.

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Posted: September 21st, 2008, 10:38pm CEST by admin

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  • Author(s): Antti V. Raisanen, Arto Lehto
  • ISBN: 9781580535427
  • Publisher: Artech House Publishers
  • Date: 27 May 2003
  • Pages: 248
this practical resource offers the first comprehensive, multidisciplinary overview of radio engineering...professionals learn important techiques to help them with the generation, control, detection, & utilization of radio waves, & find detailed guidance in radio link, amplifier, & antenna design

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Posted: September 21st, 2008, 10:38pm CEST by admin

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  • ISBN: 9780792356318
  • Publisher: Springer
  • Edition: 1
  • Date: 31 Jan 2000
  • Pages: 568
This book is mainly directed towards postgraduate students and professionals in the field of research and implementation of integrated pest and disease management programmes in greenhouse crops. After presenting the major pests and diseases that affect greenhouse vegetable and ornamental crops, several chapters deal with the tools for designing and implementing IP&DM; in protected cultivation with particular emphasis on biological control. Current implementation and the future of IP&DM; in the most important protected crops world-wide are presented in the concluding chapters.
Protected cultivation is practised in many hundreds of thousands of hectares throughout the world under quite different social, economic and technical conditions. Contributions to the book reflect such a diversity of situations: from the high-technology glasshouses of northern Europe and America to the simple plastic tunnels of the Mediterranean area and temperate eastern Asia. Furthermore, the editors have entrusted each chapter to authors whose activity and perspectives could be complementary: pathologists and entomologists, from private and public sectors, and from differentiated geographical regions. Probably no book published to date has offered such a diverse yet integrated approach to pest and disease control in greenhouse crops.
The book originated from an international course taught at the International Centre for Advanced Mediterranean Agronomic Studies in Zaragoza, Spain. The authors are specialists from universities, research institutions and companies in Europe, America, Asia, Africa and Oceania.

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Posted: September 21st, 2008, 10:38pm CEST by admin

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  • Author(s): Simon Haykin, José C. Príncipe, Terrence J. Sejnowski, John McWhirter
  • ISBN: 9780262083485
  • Publisher: The MIT Press
  • Date: 01 Oct 2006
  • Pages: 544
Signal processing and neural computation have separately and significantly influenced many disciplines, but the cross-fertilization of the two fields has begun only recently. Research now shows that each has much to teach the other, as we see highly sophisticated kinds of signal processing and elaborate hierachical levels of neural computation performed side by side in the brain. In New Directions in Statistical Signal Processing , leading researchers from both signal processing and neural computation present new work that aims to promote interaction between the two disciplines.

The book's 14 chapters, almost evenly divided between signal processing and neural computation, begin with the brain and move on to communication, signal processing, and learning systems. They examine such topics as how computational models help us understand the brain's information processing, how an intelligent machine could solve the "cocktail party problem" with "active audition" in a noisy environment, graphical and network structure modeling approaches, uncertainty in network communications, the geometric approach to blind signal processing, game-theoretic learning algorithms, and observable operator models (OOMs) as an alternative to hidden Markov models (HMMs).

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Posted: September 21st, 2008, 10:37pm CEST by admin

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  • Author(s): Sigmund Freud, Peter Gay
  • ISBN: 9780393006117
  • Publisher: W. W. Norton & Company
  • Date: 13 May 1971
  • Pages: 395
The most trivial slips of the tongue or pen, Freud believed, can reveal our secret ambitions, worries, and fantasies. The Psychopathology of Everyday Life ranks among his most enjoyable works. Starting with the story of how he once forgot the name of an Italian painter-and how a young acquaintance mangled a quotation from Virgil through fears that his girlfriend might be pregnant-it brings together a treasure trove of muddled memories, inadvertent actions, and verbal tangles. Amusing, moving, and deeply revealing of the repressed, hypocritical Viennese society of his day, Freud's dazzling interpretations provide the perfect introduction to psychoanalytic thinking in action.

Translated by Anthea Bell.
Introduction by Paul Keegan.

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Posted: September 21st, 2008, 10:37pm CEST by admin

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  • Author(s): Gerald Appel
  • ISBN: 9780131479029
  • Publisher: FT Press
  • Date: 31 Mar 2005
  • Pages: 264
"In this book, one of the world's most respected technical analysts presents a complete course in forecasting future market behavior through cyclical, trend, momentum, and volume signals. Unlike most technical analysis books, Gerald Appel's Technical Analysis offers step-by-step instructions virtually any investor can use to achieve breakthrough market success.

Appel illuminates a wide range of strategies and timing models, demystifying even advanced technical analysis for the first time. He presents technical analysis solutions for short-, intermediate-, and long-term investors, and even for mutual fund investors. Many of the strategies and models he presents have never before been published. Several are based on MACD, a tool that revolutionized technical analysis¿and one that he created.

This book distills over thirty years of trading experience into a practical guide you can start profiting from right now.

Learn technical analysis from one of the world's top experts.

Hands-on guidance from Gerald Appel, publisher of Systems and Forecasts

Coping with today's unprecedented market volatility

Indispensable techniques for profiting in uncertain markets

Winning techniques that take just 10 minutes a week

Better results than ""buy and hold""¿with far less risk

Riding the tides of market wave movement

How to recognize crucial political, seasonal, and time-based cycles

MACD: The ultimate market timing indicator invented by the author himself

Includes new, advanced breakthrough techniques that revolutionize technical analysis

How you can profit from technical analysis... step-by-step!

  • By Gerald Appel, inventor of the MACD technique used by virtually every serious technical analyst
  • How to uncover the hidden clues that reveal when markets are about to shift
  • For short-term, medium-term, and long-term investors¿including those new to technical analysis
"



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Posted: September 21st, 2008, 10:37pm CEST by admin

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  • Author(s): James Leach
  • ISBN: 9780761538059
  • Publisher: Prima Games
  • Date: 21 Nov 2001
  • Pages: 256
Heed the call of creature Isle!

• Covers the original Black & White™ plus the Creature Isle expansion pack
• Extensive strategies for every Creature Trial
• Tips for romancing Eve and completing her labors of love
• Techniques for raising your Apprentice
• Complete rundown of every new Miracle and skill
• Comprehensive details on every inch of Creature Isle

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Posted: September 21st, 2008, 10:37pm CEST by admin

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  • Author(s): Jean-Luc Prigent
  • ISBN: 9781584885788
  • Publisher: Chapman & Hall/CRC
  • Edition: 1
  • Date: 07 May 2007
  • Pages: 456
In answer to the intense development of new financial products and the increasing complexity of portfolio management theory, Portfolio Optimization and Performance Analysis offers a solid grounding in modern portfolio theory. The book presents both standard and novel results on the axiomatics of the individual choice in an uncertain framework, contains a precise overview of standard portfolio optimization, provides a review of the main results for static and dynamic cases, and shows how theoretical results can be applied to practical and operational portfolio optimization. Divided into four sections that mirror the book's aims, this resource first describes the fundamental results of decision theory, including utility maximization and risk measure minimization. Covering both active and passive portfolio management, the second part discusses standard portfolio optimization and performance measures. The book subsequently introduces dynamic portfolio optimization based on stochastic control and martingale theory. It also outlines portfolio optimization with market frictions, such as incompleteness, transaction costs, labor income, and random time horizon. The final section applies theoretical results to practical portfolio optimization, including structured portfolio management. It details portfolio insurance methods as well as performance measures for alternative investments, such as hedge funds. Taking into account the different features of portfolio management theory, this book promotes a thorough understanding for students and professionals in the field.

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Posted: September 21st, 2008, 10:37pm CEST by admin

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  • Author(s): Alain M. Robert
  • ISBN: 9780486432793
  • Publisher: Dover Publications
  • Date: 17 Oct 2003
  • Pages: 176
"This wonderful little book by Alain Robert should bring about a complete change in the learning of NSA. The author has accomplished a rare feat in the educational literature. He has succeeded in writing a book which is simple and brilliant, deep and witty, short and far-ranging. This is mathematics teaching at its best."—J.-M. Lévy-Leblond, E uropean Journal of Physics

Brief and readable, this introduction to nonstandard analysis is based on the axiomatic IST (internal set theory) approach. The two-part treatment starts with a clear, rigorous exposition of theory, followed by self-contained chapters on applications. Exercises appear at the conclusion of each chapter, with hints in addition to full solutions. Theoretical topics include idealization, standardization and transfer, real numbers and numerical functions, continuity, differentiability, and integration. Chapters involving applications cover invariant means, approximation of functions, differential equations, perturbation of a Green function, and an invariant subspaces problem. 1988 edition.


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Posted: September 21st, 2008, 10:37pm CEST by admin

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  • Author(s): Donatello Annaratone
  • ISBN: 9783540491422
  • Publisher: Springer
  • Edition: 1
  • Date: 12 Mar 2007
  • Pages: 455

This book guides through general and fundamental problems of pressure vessel design. It moreover considers problems which seem to be of lower importance but which turn out to be crucial in the design phase. The basic approach is rigorously scientific with a complete theoretical development of the topics treated, but the analysis is always pushed so far as to offer concrete and precise calculation criteria that can be immediately applied to actual designs. This is accomplished through appropriate algorithms that lead to final equations or to characteristic parameters defined through mathematical equations.

The first chapter describes how to achieve verification criteria, the second analyzes a few general problems, such as stresses of the membrane in revolution solids and edge effects. The third chapter deals with cylinders under pressure from the inside, while the fourth focuses on cylinders under pressure from the outside. The fifth chapter covers spheres, and the sixth is about all types of heads. Chapter seven discusses different components of particular shape as well as pipes, with special attention to flanges. The eighth chapter discusses the influence of holes, while the ninth is devoted to the influence of supports. Finally, chapter ten illustrates the fundamental criteria regarding fatigue analysis.

Besides the unique approach to the entire work, original contributions can be found in most chapters, thanks to the author’s numerous publications on the topic and to studies performed ad hoc for this book.



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Posted: September 21st, 2008, 10:37pm CEST by admin

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  • Author(s): Fritz Schwarz
  • ISBN: 9781584888895
  • Publisher: Chapman & Hall/CRC
  • Date: 02 Oct 2007
  • Pages: 448
Despite the fact that Sophus Lie's theory was virtually the only systematic method for solving nonlinear ordinary differential equations (ODEs), it was rarely used for practical problems because of the massive amount of calculations involved. But with the advent of computer algebra programs, it became possible to apply Lie theory to concrete problems. Taking this approach, Algorithmic Lie Theory for Solving Ordinary Differential Equations serves as a valuable introduction for solving differential equations using Lie's theory and related results. After an introductory chapter, the book provides the mathematical foundation of linear differential equations, covering Loewy's theory and Janet bases. The following chapters present results from the theory of continuous groups of a 2-D manifold and discuss the close relation between Lie's symmetry analysis and the equivalence problem. The core chapters of the book identify the symmetry classes to which quasilinear equations of order two or three belong and transform these equations to canonical form. The final chapters solve the canonical equations and produce the general solutions whenever possible as well as provide concluding remarks. The appendices contain solutions to selected exercises, useful formulae, properties of ideals of monomials, Loewy decompositions, symmetries for equations from Kamke's collection, and a brief description of the software system ALLTYPES for solving concrete algebraic problems.

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Posted: September 21st, 2008, 10:37pm CEST by admin

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  • Author(s): Berna Turam
  • ISBN: 9780804755016
  • Publisher: Stanford University Press
  • Edition: 1
  • Date: 26 Oct 2006
  • Pages: 240
Throughout the Middle East, the clash between Islamic forces and authoritarian states has undermined many democratization efforts. But in Turkey, Islamic actors—from the Gülen movement to the pro-Islamist Justice and Development Party—have been able to negotiate the terms of secular liberal democracy. This book explores the socio-political conditions and cultural venues in which Islamic movements cease to confront and start to cooperate with secular states.

Though both the Gülen and JP have ambivalent attitudes toward individual freedoms and various aspects of civil society, their continuing engagements with the state have encouraged democracy in Turkey. As they contest issues of education and morality but cooperate in ethnic and gender politics, they redraw the boundaries between public sites and private lives. Showing opportunities for engagement between Islam and the state, from Turkey to Kazakhstan to the United States, Between Islam and the State illustrates a successful means of negotiating between religion and politics.



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Posted: September 21st, 2008, 10:36pm CEST by admin

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  • Author(s): Stephen Stratton
  • ISBN: 9780761542971
  • Publisher: Prima Games
  • Date: 30 Nov 2003
  • Pages: 176
Failure is Not an Option
·Proven single-player strategy for all missions
·Detailed maps and outlines for each mission
·Tips on hostage rescue, bomb defusal, VIP Escort, and more
·Learn how to use new weapons and equipment including the M60, LAW Rocket and Shield Gun
·Killer strategies for playing as a Counter-Terrorist
·All secrets and cheats revealed
·Multiplayer strategies to make you a better online player

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Posted: September 21st, 2008, 10:36pm CEST by admin

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  • Author(s): Martha Amram
  • ISBN: 9781578514588
  • Publisher: Harvard Business School Press
  • Edition: 1
  • Date: 15 Jun 2002
  • Pages: 288
The stock market routinely values corporate growth opportunities. But inside companies, managers struggle to quantify the value of growth initiatives and to align internal valuations with those in the financial markets. Value Sweep is the first book to lay out a simple and transparent valuation method that works for the varied growth opportunities facing the modern corporation.



Based on extensive research and years of frontline work within corporations, valuation and strategy expert Martha Amram takes readers beyond the numbers, providing a new lens and a better vocabulary for envisioning, understanding, and valuing growth across a wide sweep of assets-from mature businesses to those being reshaped by intellectual property and e-commerce.



Rigorous, yet easy to use, this innovative approach allows managers to place diverse growth projects on a single "map" of value. This comparison enables them to better direct resources and attention to the most valuable projects.


Value Sweep tackles the hard valuation issues and shows:


· When to use traditional valuation methods, such as Discounted Cash Flow, and when to use more innovative methods such as decision analysis or real options


· How to quickly value growth opportunities and compare the result to sensible valuation benchmarks


· Why venture capital valuations are so sensitive to fluctuations in the stock market


· Why it is difficult to value intellectual property and how to use approximate valuation results in negotiations


· Why the simplest valuation methods work best for investments in information technology


· How to roll up project-level valuations into a corporate growth engine



AUTHORBIO: Martha Amram is an independent consultant and adviser to Fortune 500 companies and start-ups, and the author of Real Options (ISBN 0875848451, HBS Press, 1998). She lives in Palo Alto, California.




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Posted: September 21st, 2008, 10:36pm CEST by admin

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  • Author(s): Subhash C. Jain
  • ISBN: 9780759338715
  • Publisher: South-Western Pub
  • Edition: 7
  • Date: 23 Jun 2004
  • Pages: 935
Written for the capstone course in Marketing or Marketing Strategy. Marketing Planning and Strategy will help students develop strategic marketing skills essential for todayUs global competition. This text focuses on marketing stratgey from the viewpoint of the business unit and clearly distinguishes marketing strategy from marketing management.

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  • Author(s): Günther Rüdiger, Rainer Hollerbach
  • ISBN: 9783527404094
  • Publisher: Wiley-VCH
  • Edition: 1
  • Date: 03 Sep 2004
  • Pages: 343
Magnetism is one of the most pervasive features of the Universe, with planets, stars and entire galaxies all having associated magnetic fields. All of these fields are generated by the motion of electrically conducting fluids, the so-called dynamo effect. The precise details of what drives the motion, and indeed what the fluid consists of, differ widely though. In this work the authors draw upon their expertise in geophysical and astrophysical MHD to explore some of these phenomena, and describe the similarities and differences between different magnetized objects. They also explain why magnetic fields are crucial in the formation of the stars, and discuss promising experiments currently being designed to study some of the relevant physics in the laboratory. This interdisciplinary approach makes the book appealing to a wide audience in physics, astrophysics and geophysics.

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  • Author(s): Alastair I. M. Rae
  • ISBN: 9780750308397
  • Publisher: Taylor & Francis
  • Edition: 4
  • Date: 20 May 2002
  • Pages: 320

Continuing the exceptional tradition of the previous editions, Quantum Mechanics, Fourth Edition provides essential information about atomic and subatomic systems and covers some modern applications of the field. Supported by a Web page that contains a bibliography, color versions of some of the illustrations, and links to other relevant sites, the book shows how cutting-edge research topics of quantum mechanics have been applied to various disciplines. It first demonstrates how to obtain a wave equation whose solutions determine the energy levels of bound systems. The theory is then made more general and applied to a number of physical examples. Later chapters describe the connection between relativity and quantum mechanics, give some examples of how quantum mechanics has been used in information processing, and, finally, discuss the conceptual and philosophical implications of the subject. New to the Fourth Edition: · A chapter on quantum information processing that includes applications to the encryption and de-encryption of coded messages · A chapter on relativistic quantum mechanics and introductory quantum field theory · Updated material on the conceptual foundations of quantum physics containing discussions of non-locality, hidden variables, and parallel universes · Expanded information on tunneling microscopy and the Bose-Einstein condensate Presenting up-to-date information on the conceptual and philosophical aspects of quantum mechanics, this revised edition is suitable both for undergraduates studying physics, chemistry, or mathematics and for researchers involved in quantum physics.



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Posted: September 21st, 2008, 10:36pm CEST by admin

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  • Author(s): Alan Brace
  • ISBN: 9781584889687
  • Publisher: Chapman & Hall/CRC
  • Date: 01 Nov 2007
  • Pages: 240
Also known as the Libor market model, the Brace-Gatarek-Musiela (BGM) model is becoming an industry standard for pricing interest rate derivatives. Written by one of its developers, Engineering BGM builds progressively from simple to more sophisticated versions of the BGM model, offering a range of methods that can be programmed into production code to suit readers' requirements. After introducing the standard lognormal flat BGM model, the book focuses on the shifted/displaced diffusion version. Using this version, the author develops basic ideas about construction, change of measure, correlation, calibration, simulation, timeslicing, pricing, delta hedging, barriers, callable exotics (Bermudans), and vega hedging. Subsequent chapters address cross-economy BGM, the adaptation of the BGM model to inflation, a simple tractable stochastic volatility version of BGM, and Brazilian options suitable for BGM analysis. An appendix provides notation and an extensive array of formulae. The straightforward presentation of various BGM models in this handy book will help promote a robust, safe, and stable environment for calibrating, simulating, pricing, and hedging interest rate instruments.

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  • Author(s): Mark Chang
  • ISBN: 9781584889625
  • Publisher: Chapman & Hall/CRC
  • Edition: 1
  • Date: 27 Jun 2007
  • Pages: 440
Adaptive design has become an important tool in modern pharmaceutical research and development. Compared to a classic trial design with static features, an adaptive design allows for the modification of the characteristics of ongoing trials based on cumulative information. Adaptive designs increase the probability of success, reduce costs and the time to market, and promote accurate drug delivery to patients.
Reflecting the state of the art in adaptive design approaches, Adaptive Design Theory and Implementation Using SAS and R provides a concise, unified presentation of adaptive design theories, uses SAS and R for the design and simulation of adaptive trials, and illustrates how to master different adaptive designs through real-world examples. The book focuses on simple two-stage adaptive designs with sample size re-estimation before moving on to explore more challenging designs and issues that include drop-loser, adaptive dose-funding, biomarker-adaptive, multiple-endpoint adaptive, response-adaptive randomization, and Bayesian adaptive designs. In many of the chapters, the author compares methods and provides practical examples of the designs, including those used in oncology, cardiovascular, and inflammation trials.
Equipped with the knowledge of adaptive design presented in this book, you will be able to improve the efficiency of your trial design, thereby reducing the time and cost of drug development.

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  • Author(s): Elias Camouzis, G. Ladas
  • ISBN: 9781584887652
  • Publisher: Chapman & Hall/CRC
  • Date: 16 Nov 2007
  • Pages: 576
Extending and generalizing the results of rational equations,

Dynamics of Third Order Rational Difference Equations with Open Problems and Conjectures focuses on the boundedness nature of solutions, the global stability of equilibrium points, the periodic character of solutions, and the convergence to periodic solutions, including their periodic trichotomies. The book also provides numerous thought-provoking open problems and conjectures on the boundedness character, global stability, and periodic behavior of solutions of rational difference equations.

After introducing several basic definitions and general results, the authors examine 135 special cases of rational difference equations that have only bounded solutions and the equations that have unbounded solutions in some range of their parameters. They then explore the seven known nonlinear periodic trichotomies of third order rational difference equations. The main part of the book presents the known results of each of the 225 special cases of third order rational difference equations. In addition, the appendices supply tables that feature important information on these cases as well as on the boundedness character of all fourth order rational difference equations.

A Framework for Future Research

The theory and techniques developed in this book to understand the dynamics of rational difference equations will be useful in analyzing the equations in any mathematical model that involves difference equations. Moreover, the stimulating conjectures will promote future investigations in this fascinating, yet surprisingly little known area of research.



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