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The teens who became the Runaways found that some family secrets are bigger than others when they witnessed their parents, part of a cabal known as the Pride, murdering a young girl during a secret sacrificial ritual. Running away from their homes, the group banded together and began a journey of discovery, both of their parents' origins and of their own inherited powers.
Runaways Saga #1 recaps writer Brian K. Vaughn's initial run on the series... being an 18 issue vol 1, and 24 issues of volume 2... at which point Joss Whedon takes over for 6 issues...
Runaways v2 #25 - Dead End Kids [1 of 6]
Runaways v2 #26 - Dead End Kids #2 of 6