In recent years, many factors have combined to change the operating environment of the international pharmaceutical industry leading to greater specialisation and sophistication. This new edition will give an update of the different opportunities in drug discovery and development and the scientific, medical or other specialist training needed to accomplish them. The scope of this edition has been broadened to encompass all major roles, including marketing and sales.

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Good Clinical Practice Standard Operating Procedures for Clinical Researchers Edited by Josef Kolman MPRC - Medical Pharmaceutical Research Center Ltd. Vienna, Austria Paul Meng PMC - Dr Paul Meng Consultant, Vienna, Austria and Graeme Scott Professional Services in Clinical Research, Edinburgh, Scotland There is a growing trend for investigators to adopt a more formal approach to the procedures applied to various stages of clinical trials. Most environments employ some form of standard operating procedures which are designed to be used as 'working tools' within that particular field, e.g. standard operating procedures in hospitals for doctors and nurses. With rigorous standards of good clinical practice being applied to all areas, optimizing the design and use of standard operating procedures is more in demand every day. Topics covered include:

* A brief description of the history and development of clinical research and good clinical practice
* An explanation of what standard operating procedures are and how they work
* A selection of actual standard operating procedures and checklists
This well-constructed and timely work, set out in a logical, sequential order provides the necessary material needed to develop a useful set of investigator standard operating procedures.

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Let Us C 8/E (with CD-ROM) (Computer Science)(Engineering) (Computer Science) ebook for free download.

Considered to be one of the best-selling programming books ever written, the eighth edition has now been edited, revised, and updated. A CD-ROM with demos, code, compiler, executables, and MATLAB examples has been added to the book. Simplicity and an easy narration style are the hallmarks of the book, which have made its previous seven editions immensely successful. Today s C programmer (still the language of choice in science, engineering, game programming and for handheld devices) has to master the complexities of the language and contend with its usage in environments like Windows, Linux, and for the Internet. This book covers these three aspects of C programming and doesn t assume any programming background. It begins with the basics and steadily builds the pace, so the reader finds it easy to handle more complicated topics later. This popular author has crafted hundreds of excellent programming examples and exercises for every aspect of C programming. ++++Features +Self-study format provides hundreds of step by step examples and exercises + Assumes no programming knowledge; starts with the basics and progresses to more difficult topics +Includes a CD-ROM with demos, code, compiler, executables, and MATLAB examples +Covers the latest programming techniques for Windows, Linux, and the Internet ++++++Selected Topics Traditional C Programming; Pointers; Complete Build Process; Low-level File I/O; Structures, Unions, Bit-fields; Bitwise Operators. C Under Linux; Signals and Signal Handling; Blocking of Signals; Event Driven Programming; Process; PIDs; Zombies; GNOME Programming Using GTK Library. C Under Windows. Windows Programming Model; Windows Messaging Architecture; Mouse Programming; GDI. Internet Programming. CP/ IP model; Windsock Library; Building Time Clients; Whois and HTTP Clients; Sending & Receiving emails

ISBN: 1934015253, Author: Yashavant Kanetkar, Publisher: Infinity Science Press, Pages: 600, Publication Date: 2008-03-28

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Electronic Gaming Monthly August 2008
PDF | 100pages | 25.3mb(rar)
http://w14.easy-share.com/1700987529.html

 

Diabetes Management in Primary Care ebook for free download.

This book offers primary care physicians evidence-based guidelines for evaluating and treating all patients with diabetes. It covers all aspects of outpatient and hospital-based diabetes care for all age groups, and includes behavioral interventions for enhancing patient adherence. Coverage includes fine-tuning glycemic management with computerized self-blood glucose monitoring software, evaluating and treating patients with metabolic syndrome and polycystic ovary syndrome, managing mental illness in patients with diabetes, and prevention of microvascular and macrovascular complications. The book discusses newer insulin therapy protocols, insulin delivery devices such as pumps, pens, and inhaled insulin, and novel pharmacotherapies including incretin mimetics and DPP-IV inhibitors.

ISBN: 0781787629, Author: Jeff Unger, Publisher: Lippincott Williams & Wilkins, Pages: 712, Publication Date: 2007-03-01

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Stroke Prevention ebook for free download.

The treatment of stroke remains ineffective, and prevention is the key issue for this common disease. Norris and Hachinski have recruited an international group of experts to provide a comprehensive, critical review of the evidence on the primary and secondary prevention of cerebrovascular disease and to translate this information into clinical practice. The authors present fresh information on established risk factors such as atrial fibrillation, smoking and hypertension and on new risk factors such as homocysteinemia and the paradoxical role of alcohol. They cover the protective effects of lifestyle changes, diet, exercise, and estrogen. Under secondary prevention, they deal with aspirin, antiplatelet therapy, surgical measures to prevent stroke, angioplasty and stenting, and the importance of cardiac anomalies increasingly revealed by high-definition imaging. While endarterectomy remains controversial for asymptomatic carotid stenosis, it has been clearly defined as the single most effective strategy in secondary prevention. In a concluding section that will be particularly valuable to clinical readers, the authors provide a lucid, balanced discussion of how the findings from clinical trials, where patients are highly selected, closely monitored, and given the highest standard of care, can be effectively applied in the everyday practice of medicine.

ISBN: 019513382X, Author: , Publisher: Oxford University Press, USA, Pages: 368, Publication Date: 2001-04-03

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 The "bible of antenna engineering" fully updated to provide state-of-the-art coverage in antenna design and applications

Edited by John L. Volakis, one of the world's leading authorities in antenna engineering, this trusted resource covers all the classic antenna types plus many new types and designs used in communications systems, satellites, radars, and emerging applications from WLAN to automotive systems to biomedical to smart antennas.

You will also find expert discussion of topics critical to successful antenna design and engineering, such as measurement techniques and computational methods, a materials guide, wave propagation basics, microwave circuits, and matching techniques, as well as diversity and MIMO propagation models, frequency selective surfaces, and metamaterials. Packed with 1,500 illustrations, the 4th Edition of Antenna Engineering Handbook presents:

* Step-by-step guidance on most antennas (modern and classic)
* 59 chapters with 21 new chapters and 38 fully updated chapters from the previous edition
* Contributions from over 80 well-known antenna experts
* Full-color insert illustrating many commercial and military antennas

Get Quick Access to All of Today's Cutting-Edge Antennas
* Printed and Conformal Antennas
* Wideband Patch Antennas
* Wideband Arrays
* Leaky-Wave Antennas
* EBG Antennas
* UWB Antennas and Arrays
* Portable TV Antennas
* Reconfigurable Antennas
* Active Antennas
* Millimeter Wave and TeraHertz Antennas
* Fractal Antennas
* Handset and Terminal Antennas
* Biomedical Antennas
* ECM and ESM antennas
* Dielectric Resonator Antennas
* Lens Antennas
* Radiometer Antennas
* Satellite Antennas
* Reflector and Earth Station Antennas
* and Dozens More!

About the Author

John L. Volakis is the Roy and Lois Chope Chair Professor of Engineering and also serves as Director of the Electroscience Laboratory. A native of Chios, Greece, Dr. Volakis obtained his Ph.D. from The Ohio State University in 1982 and was a professor at The University of Michigan (1984-2002) prior to returning to The Ohio State University. He has co-authored over 240 journal articles and 350 conference papers, and is co-author of the books: Approximate Boundary Conditions in Electromagnetics (IEE Press) Finite Element Method for Electromagnetics (IEEE Press-Wiley), and Frequency Domain Hybrid Finite Element Methods in Electromagnetics (Morgan & Claypool). Dr. Volakis is a Fellow of IEEE and a former President of the IEEE Antennas and Propagation Society. He graduated/mentored over 50 Ph.D. students/post-docs and is listed by ISI among the top 250 most referenced authors in Engineering/Computer Science.

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Design for Emergence: Collaborative Social Play with Online and Location-Based Media, Volume 153 Frontiers in Artificial Intelligence and Applications ebook for free download.

Design for Emergence investigates spontaneous, unpredictable uses of technology that are driven by social contexts and collaborative processes, based on our ability to communicate our presence, both virtual and physical, in symbolic ways. In light of the fact that social dynamics and unexpected uses of technology can inspire innovation, this book proposes a research model of design for emergence, focusing on emergent phenomena as part of an iterative design process. By providing playful, technology-mediated experiences with minimal structure, unpredictable user behaviors can emerge through exploration, resulting in a richer and more complex, social experience. The research methodology is practice-based; two interactive prototypes were designed, implemented and evaluated in different contexts: an online multiplayer BumperCar game and a wireless, location-based urban game of 'tag', called CitiTag. User studies showed that collaborative, spontaneous play can enhance the sense of social participation in a group activity. Collective and individual behaviors and creative uses of technology emerged from a simply designed application based on symbolic presence, both in the virtual and the physical world. CitiTag experiments showed that virtual elements in a mixed reality game can instigate novel experiences in the context of our everyday physical and social environment, with often unexpected results. The observed emergent behaviors are personal and collective extensions of the virtual experience in the real world. The book concludes with a positive view of ubiquitous and social computing, in which the virtual world becomes a 'first class citizen' rather than a substitute for the real world, creating new situations and engaging experiences in the setting of our daily life that were not possible before.

ISBN: 1586037013, Author: Yanna Vogiazou, Publisher: IOS Press, Pages: 192, Publication Date: 2007-01-01

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 * Hardcover: 448 pages
* Publisher: CRC (November 9, 2005)
* Language: English
* ISBN-10: 084935725X
* ISBN-13: 978-0849357251

Product Description
Surveying the technologies used to satisfy the world's demand for open, efficient, and clean electricity, Synchronous Generators provides an in-depth examination of synchronous generators for both stand-alone and grid-connected applications. Part of The Electric Generators Handbook, Two-Volume Set, this book offers authoritative, tightly focused treatment of the topologies, steady state and transients modeling, performance, control, design, and testing of stand-alone and grid-connected generators in synchronous operation. Synchronous Generators offers a thorough introduction to electrical energy and electricity generation, including the basic principles of electric generators. The book devotes a chapter to the most representative prime mover models for transients used in active control of various generators. Then, individual chapters explore the topologies and steady state of large and medium-power synchronous generators; modeling and transients; control in power systems; design, including simple cases; and testing. Numerous examples, sample results, and illustrations highlight the concepts. The promise of renewable, sustainable energy rests on our ability to design innovative power systems that are able to harness energy from a variety of sources. Synchronous Generators supplies the tools necessary to design, validate, and deploy the right power generation technologies to fulfill tomorrow's complex energy needs.

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Evidence-Based Eye Care ebook for free download.

This volume offers every clinical ophthalmologist valuable guidance in implementing the results of the latest multicenter clinical trials in practice. Chapters on all major disease entities review all pertinent trials, bring these trials into a real-world setting, and show how the results should influence day-to-day patient management. Coverage includes diseases in all ophthalmologic subspecialties--cornea/external disease, glaucoma, retina, pediatric ophthalmology, ocular oncology, neuro-ophthalmology, and oculoplastics. More than 170 illustrations, 92 in full color, complement the text. General ophthalmologists will have at their fingertips, in an easily digestible format, the current standard of patient care across the spectrum of ophthalmology.

ISBN: 0781769647, Author: , Publisher: Lippincott Williams & Wilkins, Pages: 336, Publication Date: 2006-11-01

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 * Paperback: 432 pages
* Publisher: Wrox (April 28, 2008)
* Language: English
* ISBN-10: 0470147563
* ISBN-13: 978-0470147566

Product Description
This first technical title of its kind, this is a revolutionary book for the object oriented developer. It takes the reader through the intense process of building a real-world application using Domain-Driven Design principles implemented in C# 3.0 (.NET Framework 3.5). The reader is introduced to a business domain of a real-world Construction Administration application for an architecture firm. The application is ma critical, legacy MS Access application that has outgrown MS Access and is ready to become a full-fledged enterprise application. In each chapter, the relevant part of the domain is modeled out via diagrams and code. The application is built using C#, Windows Presentation Foundation, and other Microsoft technologies and best practices. The main focus of the book is on designing and implementing the domain model and all of the supporting patterns and framework that are built in support of the domain model. The emphasis is on these theories in action through the working application, not on the tools used. The main goal is to show how to take a set of requirements and user scenarios and apply Domain-Driven Design principles to the requirements in order to create a domain model that satisfies both the user requirements and the system requirements. Various patterns are introduced along the way in order to aid with certain activities such as adapting the domain model to the user interface, synchronizing data between the client and the server, validation, mapping, etc. Although this particular application is a WPF application, most of the design patterns introduced and applied in the book can be used on other types of applications, such as web applications, web services, etc.

With the Problem-Design-Solution promise and approach, the chapters are broken down into their own modules where the intent is to take the reader through the process from beginning to end while building a complete project with each chapter module. Each chapter establishes the problem, what the reader wants to do, and why it is important, and then what factors and restrictions need to be taken into account. Next the chapter covers how the programmer will solve the problem with an adequate solution that will provide only the best results. Finally, the developer produces code and other materials to better realize the design and solution to the problem. This part of the chapter is where the reader gets hands-on practice at creating code that builds applications.

From the Back Cover
.NET Domain-Driven Design with C# Problem Design Solution

As the first technical book of its kind, this unique resource walks you through the process of building a real-world application usingDomain-Driven Design implemented in C#. Based on a real application for an existing company, the project featured throughout the book focuses on the Domain Model and the framework that is being built to support it.

Each chapter is broken down into specific modules so that you can identify the problem, decide what solution will provide the best results, and then execute that design to solve the problem. With each chapter, you?ll build a complete project from beginning to end, offering you indispensable, hands-on practice at creating code that builds applications.

What you will learn from this book

* When, why, and how to use Domain-Driven Design
* How to design and build the initial Domain Model
* What to do to achieve ?Persistence Ignorance?
* Ways to build a Repository framework for the Domain Model
* Techniques for applying TDD to the Domain Model
* How to apply the Model-View-ViewModel Pattern
* How to build a client-side membership system
* What to do to synchronize the client application with the server

Who this book is for
This book is for experienced C# .NET developers who want to improve their techniques for writing applications that perform well and are highly scalable.

Wrox Problem - Design - Solution references give you solid, workable solutions to real-world development problems. Each is devoted to a single application, analyzing every problem, examining relevant design issues, and implementing the ideal solution.

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 * Paperback: 1420 pages
* Publisher: Wrox (May 5, 2008)
* Language: English
* ISBN-10: 0470191368
* ISBN-13: 978-0470191361


Product Description
Professional Visual Basic 2008

The 2008 version of Visual Basic is tremendously enhanced and introduces dramatic new concepts, techniques, and features to this popular object-oriented language. Written by an elite author team who are sympathetic to the challenges of learning VB 2008, this comprehensive book provides a clear and concise approach to using VB 2008 in the ever-expanding .NET world.

This book focuses on using the latest and most powerful tools from the Microsoft arsenal within your Visual Basic solutions. Looking closely at LINQ, AJAX, a new Visual Studio and more, you'll be able to take lessons from this book and apply them to what you are doing today. You'll examine everything from the .NET Framework to the best practices for deploying .NET applications to database access and integrating with other technologies, such as COM and XML.

What you will learn from this book

* The core elements of VB 2008 as well as full syntax of all the new additions the language offers
* Ways that the Common Language Runtime (CLR) is responsible for managing the execution of code compiled on the .NET platform
* How VB is used in the creation, installation, running, and debugging of Windows® Services
* How to work with the new SQL Server 2008 along with your .NET applications
* The many features of Windows Forms and Windows Presentation Foundation
* Ways to take advantage of the abilities of LINQ
* The new web technology introduced by Silverlight

Who this book is for
This book is for experienced developers who are looking to transition to the latest version of Visual Basic.

Wrox Professional guides are planned and written by working programmers to meet the real-world needs of programmers, developers, and IT professionals. Focused and relevant, they address the issues technology professionals face every day. They provide examples, practical solutions, and expert education in new technologies, all designed to help programmers do a better job.

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