By

• Publisher:   Thieme Medical Publishers
• Number Of Pages:   488
• Publication Date:   2002-12-15
• Sales Rank:   405825
• ISBN / ASIN:   0865779155
• EAN:   9780865779150
• Binding:   Hardcover
• Manufacturer:   Thieme Medical Publishers
• Studio:   Thieme Medical Publishers
• Average Rating:  
• Total Reviews:  

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Childhood tuberculosis an Issue of Paediatric Respiratory Reviews
  Volume 8, Issue 2, Pages 97-184 (June 2007)  ASIN: B00007B0C5 Publisher: Elsevier  
 
Childhood tuberculosis: new recognition of an old disease
Childhood tuberculosis – global epidemiology and the impact of HIV
Clinical manifestations of tuberculosis in children
Airway involvement in pulmonary tuberculosis
New approaches and emerging technologies in the diagnosis of childhood tuberculosis
Old and new drugs for the treatment of tuberculosis in children
Tuberculosis and human immunodeficiency virus co-infection in children: management challenges
Childhood tuberculosis: old and new vaccines
Vocal cord dysfunction in children
Treatment approaches for empyema in children
The European Regulation on medicines for paediatric use

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By

• Publisher:   Oxford University Press, USA
• Number Of Pages:   758
• Publication Date:   2000-02-15
• Sales Rank:   587012
• ISBN / ASIN:   0195119363
• EAN:   9780195119367
• Binding:   Hardcover
• Manufacturer:   Oxford University Press, USA
• Studio:   Oxford University Press, USA
• Average Rating:   5
• Total Reviews:   1

Book Description:

This Second Edition reverses the usual growth curve by reducing the number of chapters from 50 to 44, mainly by amalgamating the coverage of infectious diseases. The book has been completely reorganized so that chapters are now grouped by type of disorder. In a thorough updating, many chapters have been rewritten by different authors and two new chapters on medico-legal aspects and economic outcomes research have been added. As before, the book addresses the important clinical questions: what is the natural history of the disorder and how does medical or surgical treatment alter the outcome? The authors provide clinical prediction rules and a detailed critical review of prognostic factors. Patients and their families are increasingly demanding information on the prognosis of disease, and there is no better reference source for neurologists and neurosurgeons to use on a daily basis than this volume.


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By

• Publisher:   Elsevier Science
• Number Of Pages:   482
• Publication Date:   2007-03-26
• Sales Rank:   364762
• ISBN / ASIN:   0444528555
• EAN:   9780444528551
• Binding:   Hardcover
• Manufacturer:   Elsevier Science
• Studio:   Elsevier Science
• Average Rating:  
• Total Reviews:  

Book Description:

This book is organized into 4 sections, each looking at the question of outcome prediction in cancer from a different angle. The first section describes the clinical problem and some of the predicaments that clinicians face in dealing with cancer. Amongst issues discussed in this section are the TNM staging, accepted methods for survival analysis and competing risks. The second section describes the biological and genetic markers and the rôle of bioinformatics. Understanding of the genetic and environmental basis of cancers will help in identifying high-risk populations and developing effective prevention and early detection strategies. The third section provides technical details of mathematical analysis behind survival prediction backed up by examples from various types of cancers. The fourth section describes a number of machine learning methods which have been applied to decision support in cancer. The final section describes how information is shared within the scientific and medical communities and with the general population using information technology and the World Wide Web.

* Applications cover 8 types of cancer including brain, eye, mouth, head and neck, breast, lungs, colon and prostate
* Include contributions from authors in 5 different disciplines
* Provides a valuable educational tool for medical informatics


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By

• Publisher:   Academic Press
• Number Of Pages:   696
• Publication Date:   2006-12-11
• Sales Rank:   2887324
• ISBN / ASIN:   0123694159
• EAN:   9780123694157
• Binding:   Hardcover
• Manufacturer:   Academic Press
• Studio:   Academic Press
• Average Rating:  
• Total Reviews:  

Book Description:

There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy.

Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and detailed description of clinical success stories to date, as well as insights into the road ahead. As highlighted by this timely and authoritative survey, scale-up technologies and whole organ transplantation are among the hurdles representing the next frontier.

The contents are organized into four main sections, with the first covering basic biology, including transplant immunology, the use of immunosuppressive drugs, stem cell biology, and the development of donor animals for transplantation. The next part looks at peripheral and reconstructive applications, followed by a section devoted to transplantation for diseases of the central nervous system. The last part presents efforts to address the key challenges ahead, such as identifying novel transplantable cells and integrating biomaterials and nanotechnology with cell matrices.

· Provides detailed description of clinical trials in cell transplantation
· Review of current therapeutic approaches
· Coverage of the broad range of diseases addressed by cell therapeutics
· Discussion of stem cell biology and its role in transplantation


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By

• Publisher:   Academic Press
• Number Of Pages:   432
• Publication Date:   2006-12-19
• Sales Rank:   1238966
• ISBN / ASIN:   0120066963
• EAN:   9780120066964
• Binding:   Hardcover
• Manufacturer:   Academic Press
• Studio:   Academic Press
• Average Rating:  
• Total Reviews:  

Book Description:

The Advances in Cancer Research series provides invaluable information on the exciting and fast-moving field of cancer research. This volume stands as the first ever thematic volume in the series, focusing on the topic of genomics in cancer drug development. The chapters included in this book represent the cutting-edge information in the field and span such topics as Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics; Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches; The Application of siRNA Technology to Cancer Biology Discovery; Ribozyme Technology for Cancer Gene Target Identification and Validation; Cancer Cell-Based Genomic and Small Molecule Screens; Tumour Antigens as Surrogate Markers and Targets for Therapy and Vaccines; Practices and Pitfalls of Mouse Cancer Models in Drug Discovery; Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development Quantification of Emerging Protein Biomarkers; Molecular Optical Imaging of Therapeutic Targets of Cancer; Cancer Drug Approval in the United States, Europe and Japan.

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By Neal Nathanson

• Publisher:   Academic Press
• Number Of Pages:   280
• Publication Date:   2007-04-04
• Sales Rank:   612511
• ISBN / ASIN:   0123694647
• EAN:   9780123694645
• Binding:   Paperback
• Manufacturer:   Academic Press
• Studio:   Academic Press
• Average Rating:  
• Total Reviews:  

Book Description:

Based on the highly successful reference work Viral Pathogenesis published in 1997, this concise, economical version can be used both as an introductory text or for self-education by medical students and biologists alike. This latest edition provides a completely revised overview of the subject with new chapters on innate immunity, emerging viral diseases, and antiviral therapy in a format that is easy to understand without continually referring to additional information. Used by the author in his graduate classes at the University of Pennsylvania, it sets forth the essential principles and discusses the details of how the immune system responds to viral invasion including the treatment and prevention of infection. Illustrated by pertinent examples it is one of the only books devoted exclusively to this topic.

* Offers almost a 20% expansion over the first edition
* Focuses specifically on viral pathogenesis unlike other texts where only a few chapters are devoted to the topic
* Neal Nathanson is one of the primary authorities in the field and has authored chapters on viral pathogenesis in two of the most well known virology and microbiology titles Field's Virology and Topley and Wilson's Microbiology
* Now in four color throughout!

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By

• Publisher:   Oxford University Press, USA
• Number Of Pages:   338
• Publication Date:   2003-09-05
• Sales Rank:   1051356
• ISBN / ASIN:   0195141091
• EAN:   9780195141092
• Binding:   Hardcover
• Manufacturer:   Oxford University Press, USA
• Studio:   Oxford University Press, USA
• Average Rating:  
• Total Reviews:  

Book Description:

Selling Points - Presents the newest theoretical and empiral advances in the domain Relates clinical impliations and applications to basic research issues Gathers contributions in different sub-fields thate are rarely presented jointly During the past 25 years, the study of nonverbal behavior has become a signifcant subarea of psychology. Employing a variety of approaches and encompassing numerous perspectives, researchers have made important theoretical and empirical strides in discovering the origins, functions, and consequences of nonverbal behavior. This research has clearly shown that nonverbal behavior plays a far greater role than merely reflecting emotional experience -- it also plays a central role in psychological adaptation. This volume presents, in an integrated framework, contemporary perspectives on the role of nonverbal behavior in psychological regulation, adaptation, and psychopathology, and includes both empirical and theoretical research that is central to our understanding of the reciprocal influences between nonverbal behavior, psychopathology, and therapeutic processes. It has several objectives: One is to present fundamental theories and data relevant to researchers and clinicians working in such fields as psychopathology and psychotherapy. Another objective is to link contributions of basic research to clinical applications. Finally, the volume gathers contributions in different sub-fields that are rarely presented jointly, such as brain damage and non-verbal skills.

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By

• Publisher:   Springer
• Number Of Pages:   435
• Publication Date:   2007-07
• Sales Rank:  
• ISBN / ASIN:   1402058667
• EAN:   9781402058660
• Binding:   Hardcover
• Manufacturer:   Springer
• Studio:   Springer
• Average Rating:  
• Total Reviews:  

Book Description:

Metastasis (spread of cancer in the body) is the main cause of death for patients with breast cancer, the leading female tumour in the industrialised countries and developing countries alike. The biology and treatment of breast cancer metastasis remains an active area of scientific and clinical investigation.

Written by experts in the subject area, the book has covered a broad range of topics in the metastasis of breast cancer, from genetics, biology to clinical management. Main topics include genetic control, biology, growth factors, cell adhesion, cell motility and invasion, natures of bone metastasis, sentinel node therapies, hormonal links, new biomarkers and detection of micrometastasis, and diagnosis The book also covers the current treatment options including surgical management, chemotherapy and hormonal therapies. This timely book provides the current knowledge in the area of breast cancer metastasis and will be of important reading material for oncologists, radiologists, cancer researchers, biologists and health worker.

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By Tony Hope

• Publisher:   Oxford University Press, USA
• Number Of Pages:   170
• Publication Date:   2004-10-13
• Sales Rank:   174380
• ISBN / ASIN:   0192802828
• EAN:   9780192802828
• Binding:   Paperback
• Manufacturer:   Oxford University Press, USA
• Studio:   Oxford University Press, USA
• Average Rating:  
• Total Reviews:  

Book Description:

Issues in medical ethics are rarely out of the media and it is an area of ethics that has particular interest for the general public as well as the medical practitioner. This short and accessible introduction provides an invaluable tool with which to think about the ethical values that lie at the heart of medicine. Tony Hope deals with the thorny moral questions such as euthanasia and the morality of killing, and also explores political questions such as: how should health care resources be distributed fairly? Each chapter in this book considers a different issue: genetics, modern reproductive technologies, resource allocation, mental health, medical research, and discusses controversial questions such as: DT Who should have access to reproductive technology? Who should pay? DT Is it right to fund expensive drug treatment for individuals? DT Should active euthanasia be legalized? DT Should treatment for mental illness be imposed on patients without their consent? DT Who should have access to information from genetic testing? DT Should we require consent for use of dead bodies or organs in medical research?

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By Mahmoud H. Hamdan

• Publisher:   Wiley-Interscience
• Number Of Pages:   377
• Publication Date:   2007-02-09
• Sales Rank:   334144
• ISBN / ASIN:   0471745162
• EAN:   9780471745167
• Binding:   Hardcover
• Manufacturer:   Wiley-Interscience
• Studio:   Wiley-Interscience
• Average Rating:  
• Total Reviews:  

Book Description:

Tools, techniques, and progress in cancer biomarkers discovery

The completion of a number of gene sequencing projects, recent advances in genomic and proteomic technologies, and the availability of powerful bioinformatics tools have led to promising new avenues and approaches in the search for cancer biomarkers. This book provides a comprehensive overview of current methodologies and technologies. It discusses biomarker discovery as a whole, rather than focusing on one specific marker or cancer. With information on both existing and potential biomarkers, Cancer Biomarkers: Analytical Techniques for Discovery:
* Provides insights into the current technological platforms for biomarker discovery, including mass spectrometry combined with multidimensional chromatography, DIGE, and various chip technologies
* Includes a detailed discussion of protein networks and protein phosphorylation in cancer
* Details the use of imaging mass spectrometry, laser capture microdissection, serial analysis of gene expression, enzyme-linked immunosorbent assays, protein microarrays, antibody-based microarrays, and bioinformatics
* Covers the emerging role of surface-enhanced laser desorption ionization (SELDI) and various tagging and labeling strategies
* Discusses related regulatory and ethical issues

With a wealth of information that can be applied to a broad spectrum of biomarker research projects, this is a core reference for biomarker researchers, scientists working in proteomics and bioinformatics, pharmaceutical scientists, oncologists, biochemists, biologists, and chemists.



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By John M. Butler

• Publisher:   Academic Press
• Number Of Pages:   688
• Publication Date:   2005-02-22
• Sales Rank:   28792
• ISBN / ASIN:   0121479528
• EAN:   9780121479527
• Binding:   Hardcover
• Manufacturer:   Academic Press
• Studio:   Academic Press
• Average Rating:   5
• Total Reviews:   7

Book Description:

Since the enormously successful first edition of Forensic DNA Typing was published, the Human Genome Project has published a draft sequence of the human genome and completed the finished reference sequence. The advent of modern DNA technology has resulted in the increased ability to perform human identity testingdesirable in a number of situations including the determination of perpetrators of violent crime such as murder and rape, resolving unestablished paternity, and identifying remains of missing persons or victims of mass disasters. The technology has been utilized in identifying remains from victims of the World Trade Center twin towers collapse following the terrorist attacks of September 11, 2001, the President Clinton-Monica Lewinsky scandal, and the identification of the remains in the Tomb of the Unknown Soldier. Indeed, our perceptions of history have been changed with DNA evidence that revealed Thomas Jefferson fathered a child by one of his slaves. This book examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century.

*The only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome
*Chapters cover the topic from introductory level right up to "cutting edge" research
*High-profile cases are addressed throughout the book, near the sections dealing with the science or issues behind these cases
*NEW TO THIS EDITION: D.N.A. Boxes--boxed "Data, Notes & Applications" sections throughout the book offer higher levels of detail on specific questions



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By Richard K Riegelman

• Publisher:   Lippincott Williams & Wilkins
• Number Of Pages:   328
• Publication Date:   2004-10-01
• Sales Rank:   91435
• ISBN / ASIN:   0781745764
• EAN:   9780781745765
• Binding:   Paperback
• Manufacturer:   Lippincott Williams & Wilkins
• Studio:   Lippincott Williams & Wilkins
• Average Rating:   4
• Total Reviews:   1

Book Description:

Now in its Fifth Edition, this best-selling text presents a step-by-step approach to critical and efficient reading of the medical literature. Health care professionals will learn how to evaluate clinical studies, identify flaws in study design, interpret statistics, and apply evidence from clinical research in practice. This edition�s new section, Guide to the Guidelines, reflects the growing use and importance of clinical guidelines. The outcomes research chapter includes concepts of safety and effects of interactions on outcomes. This edition also presents statistics more graphically. Unique learning aids include question checklists, scenarios illustrating study design, and flaw-catching exercises, plus a StudyingaStudy.com Website providing interactive materials.

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By Donald A Wiss

• Publisher:   Lippincott Williams & Wilkins
• Number Of Pages:   832
• Publication Date:   2006-03-01
• Sales Rank:   66445
• ISBN / ASIN:   0781752906
• EAN:   9780781752909
• Binding:   Hardcover
• Manufacturer:   Lippincott Williams & Wilkins
• Studio:   Lippincott Williams & Wilkins
• Average Rating:   5
• Total Reviews:   2

Book Description:

Completely updated for its Second Edition, this acclaimed Master Techniques in Orthopaedic Surgery volume presents the most advanced, successful surgical techniques for fractures of the upper extremity, lower extremity, pelvis, and acetabulum. The world's foremost surgeons describe their preferred techniques in step-by-step detail, explain the indications and contraindications, identify pitfalls and potential complications, and offer pearls and tips for improving results. The book is thoroughly illustrated with full-color, sequential, surgeon's-eye view intraoperative photographs, as well as drawings by noted medical illustrators.



This edition includes nine new chapters­Clavicle Fractures: ORIF; Femoral Neck Fractures: Arthroplasty; Intertrochanteric Hip Fractures: IM Hip Screw; Hip Arthroplasty for Intertrochanteric Hip Fractures; Femoral Shaft Fractures: Retrograde Nailing; Supracondylar Femur Fractures: ORIF; Proximal Tibial Fractures: Locked Plating; Tibial Shaft Fractures: Spatial Frame; and Periprosthetic Femur Fractures. Seventeen chapters have been rewritten by new contributing authors.


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